Regina Joyce Pezzulo

Regina Pezzulo ObituaryObituary published on Legacy.com by O'Brien Funeral Home - South Boston on Mar. 3, 2026.Regina Joyce (Clougherty) Pezzulo of South Boston passed away peacefully on February 27,2026. She was 86.She was born in Boston on February 9, 1940 to the late John and Regina (Czarnecki) Clougherty.Regina was the beloved wife of the late Anthony P. Pezzulo, the devoted mother of Dr. Gayle Pezzulo and Joyce (Pezzulo) Coffey, the cherished Nana of Ava Coffey, and the loving sister of the late Jack Clougherty.A woman of strength who faced life's challenges with resilience and grace, always putting family first. Her legacy lives in the values she instilled, the poise and elegance she displayed, and the love she gave. She will be deeply missed and forever remembered.We would like to extend our gratitude to the home caregivers who showed tremendous compassion, respect, and dignity to her throughout her battle with Alzheimer's Disease.Visitation in the O'Brien Funeral Home 146 Dorchester St South Boston on Thursday March 5th from 11am -12pm. Followed by funeral service at 12pm relatives and friends are kindly invited to attend. Interment Cedar Grove Cemetery, Dorchester. For directions and guest book please visit www.obrienfunerals.comTo plant trees in memory, please visit the Sympathy Store.